BDBM50127166 10-hydroxy-4-phenethyl-17-(3-phenylpropoxy)-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-trien-14-one

SMILES Oc1ccc2CC3N(CCc4ccccc4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35OCCCc1ccccc1

InChI Key InChIKey=IGJGVONOVSZTLU-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50127166   

TargetKappa-type opioid receptor(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50127166(10-hydroxy-4-phenethyl-17-(3-phenylpropoxy)-(13R,1...)
Affinity DataKi:  0.600nMAssay Description:In vitro binding affinity at opioid receptor kappa 1 was determined in human CHO cells using [3H]U-69593More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50127166(10-hydroxy-4-phenethyl-17-(3-phenylpropoxy)-(13R,1...)
Affinity DataKi:  1.10nMAssay Description:In vitro binding affinity at opioid receptor mu 1 was determined in C6 rat glioma cells using [3H]DAMGOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50127166(10-hydroxy-4-phenethyl-17-(3-phenylpropoxy)-(13R,1...)
Affinity DataKi:  1.25nMAssay Description:In vitro binding affinity at opioid receptor delta 1 was determined in C6 rat glioma cells using [3H]Ile5,6 deltorphin IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed