BDBM50129547 5-Biphenyl-4-yl-1-(2,4-dichloro-phenyl)-1H-pyrazole-3-carboxylic acid::CHEMBL306353

SMILES OC(=O)c1cc(-c2ccc(cc2)-c2ccccc2)n(n1)-c1ccc(Cl)cc1Cl

InChI Key InChIKey=XPIHGXBSMIVTBJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50129547   

TargetMethionine--tRNA ligase, cytoplasmic(Human)
Cubist Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50129547(5-Biphenyl-4-yl-1-(2,4-dichloro-phenyl)-1H-pyrazol...)
Affinity DataIC50: 4.09E+4nMAssay Description:Inhibitory activity against Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethionine--tRNA ligase, cytoplasmic(Human)
Cubist Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50129547(5-Biphenyl-4-yl-1-(2,4-dichloro-phenyl)-1H-pyrazol...)
Affinity DataIC50: 4.43E+4nMAssay Description:Inhibitory activity against human methionyl-tRNA synthetase (hMetRS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed