BDBM50129552 1-(2,4-Dichloro-phenyl)-5-(4'-fluoro-biphenyl-4-yl)-1H-pyrazole-3-carboxylic acid::CHEMBL304623

SMILES OC(=O)c1cc(-c2ccc(cc2)-c2ccc(F)cc2)n(n1)-c1ccc(Cl)cc1Cl

InChI Key InChIKey=CJYADRABSMIPKS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50129552   

TargetMethionine--tRNA ligase, cytoplasmic(Human)
Cubist Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50129552(1-(2,4-Dichloro-phenyl)-5-(4'-fluoro-biphenyl-4-yl...)
Affinity DataIC50: 4.13E+4nMAssay Description:Inhibitory activity against human methionyl-tRNA synthetase (hMetRS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethionine--tRNA ligase, cytoplasmic(Human)
Cubist Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50129552(1-(2,4-Dichloro-phenyl)-5-(4'-fluoro-biphenyl-4-yl...)
Affinity DataIC50: 4.32E+4nMAssay Description:Inhibitory activity against Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed