BDBM50133630 (3Z)-5-iodo-1H-indole-2,3-dione 3-thiosemicarbazone::CHEMBL119370

SMILES NC(=S)N=Nc1c(O)[nH]c2ccc(I)cc12

InChI Key InChIKey=HCLAUXCJQUNKKP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50133630   

TargetCruzipain(Trypanosoma cruzi)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM50133630((3Z)-5-iodo-1H-indole-2,3-dione 3-thiosemicarbazon...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against Trypanosoma brucei rhodesiense cysteine protease rhodesainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM50133630((3Z)-5-iodo-1H-indole-2,3-dione 3-thiosemicarbazon...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibitory activity against the Trypanosoma cruzi cysteine protease cruzainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM50133630((3Z)-5-iodo-1H-indole-2,3-dione 3-thiosemicarbazon...)
Affinity DataIC50: 2.87E+4nMAssay Description:Inhibitory activity against Falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed