BDBM50136596 3-[(3R,4R)-3,4-Dimethyl-1-(3-phenyl-butyl)-piperidin-4-yl]-benzamide::CHEMBL139180

SMILES CC(CCN1CC[C@](C)([C@@H](C)C1)c1cccc(c1)C(N)=O)c1ccccc1

InChI Key InChIKey=HYNYFKQSCKKARU-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50136596   

TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50136596(3-[(3R,4R)-3,4-Dimethyl-1-(3-phenyl-butyl)-piperid...)
Affinity DataKi:  5nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50136596(3-[(3R,4R)-3,4-Dimethyl-1-(3-phenyl-butyl)-piperid...)
Affinity DataKi:  100nMAssay Description:Binding affinity at cloned human kappa opioid receptor by [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50136596(3-[(3R,4R)-3,4-Dimethyl-1-(3-phenyl-butyl)-piperid...)
Affinity DataKi:  310nMAssay Description:Inhibition of [3H]diprenorphine binding to the cloned human delta opioid receptors using 10 uM concentration of the compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed