BDBM50137542 CHEMBL178066::N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-5-yl]-4-fluoro-benzamide

SMILES CN(C)CCc1c(C)[nH]c2ccc(NC(=O)c3ccc(F)cc3)cc12

InChI Key InChIKey=IIHVBDVYBDSPPU-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50137542   

Target5-hydroxytryptamine receptor 1F(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50137542(N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-5-y...)
Affinity DataKi:  8.20nMAssay Description:Binding affinity to 5-HT1F (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50137542(N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-5-y...)
Affinity DataKi:  8.20nMAssay Description:In vitro binding affinity for human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50137542(N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-5-y...)
Affinity DataKi: >260nMAssay Description:Binding affinity to 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50137542(N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-5-y...)
Affinity DataKi: >260nMAssay Description:Binding affinity to 5-HT1D (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50137542(N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-5-y...)
Affinity DataKi: >260nMAssay Description:Binding affinity to 5-HT2B (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50137542(N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-5-y...)
Affinity DataKi: >260nMAssay Description:Binding affinity to 5-HT1A (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50137542(N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-5-y...)
Affinity DataKi: >260nMAssay Description:Binding affinity to 5-HT5A receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50137542(N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-5-y...)
Affinity DataKi: >260nMAssay Description:Binding affinity to 5-HT1B (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50137542(N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-5-y...)
Affinity DataKi: >260nMAssay Description:Binding affinity to 5-HT2C (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed