BDBM50139013 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::(S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide::1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylicacid[1-((S)-(S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL333357::H-Tyr-Pro-Phe-Phe-NH2::Tyr-Pro-Phe-Phe-NH2::endomorphin-2

SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key InChIKey=XIJHWXXXIMEHKW-UHFFFAOYSA-N

Data  66 KI  42 IC50  17 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 125 hits for monomerid = 50139013   

TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  0.00950nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Medical University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataEC50:  0.0400nMAssay Description:Activity at mu opioid receptor assessed as increase in calcium level in CHO cells by aequorin luminescence based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Medical University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataEC50:  0.0400nMAssay Description:Antagonist activity at mu opioid receptor expressed in CHO cells assessed as release of intracellular calcium ions by aequorin luminescence-based cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  0.490nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 0.680nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  0.690nMAssay Description:Displacement of [3H]DAMGO from Wistar rat brain membrane MOPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Medical University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  0.690nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 0.690nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  0.690nMAssay Description:Binding affinity against rat brain Opioid receptor mu 1 using [3H]DAMGO radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 0.790nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 0.790nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 0.790nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 0.790nMAssay Description:Displacement of [3H]DAMGO from MOR in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 0.990nMAssay Description:Displacement of [3H]DAMGO from Wistar rat mu opioid receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Medical University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]endomorphin-2 from mu opioid receptor in Wistar rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  1.33nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosome membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  1.33nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain P2 synaptosomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  1.35nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Medical University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at human recombinant MOP expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Guinea pig)
Clinical Research Institute of Montreal

Curated by PDSP Ki Database
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  2.06nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  2.06nMAssay Description:Binding affinity towards mu receptor in rat brain using [3H]DAMGOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Medical University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]DAMGO from human recombinant MOR expressed in CHO cell membranes incubated for 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]DAMGO from rat cortex mu opioid receptor after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Medical University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu opioid receptor expressed in HEK293 cells after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 3.46nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  3.70nMAssay Description:Inhibition of [3H]naloxone binding to rat brain homogenate Opioid receptor muMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]endomorphin-2 from Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Clinical Research Institute of Montreal

Curated by PDSP Ki Database
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 4.70nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Medical University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in CHO cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Medical University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataEC50:  5.80nMAssay Description:Agonist activity at human recombinant MOR expressed in CHO cells co-expressing C-terminally modified Galphaqi5 assessed as induction of calcium mobil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  6.10nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Clinical Research Institute of Montreal

Curated by PDSP Ki Database
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 6.88nMAssay Description:Agonist activity at mu opioid receptor in Hartley guinea pig intestine assessed as inhibition of electrically evoked myenteric plexus longitudinal mu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Clinical Research Institute of Montreal

Curated by PDSP Ki Database
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 6.90nMAssay Description:Agonist activity at mu opioid receptor in Hartley guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Clinical Research Institute of Montreal

Curated by PDSP Ki Database
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 7.70nMAssay Description:Agonist activity at mu opioid receptor by inhibition of electrically evoked muscle contraction in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  8.23nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane after 3 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  8.23nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  8.23nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Medical University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  8.23nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  8.70nMAssay Description:Displacement of [3H]SP1-7 from NK1 receptor in Sprague-Dawley rat spinal cord membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2020
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  8.70nMAssay Description:Displacement of [3H]SP1-7 from NK1 receptor in Sprague-Dawley rat spinal cord membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Clinical Research Institute of Montreal

Curated by PDSP Ki Database
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 9.22nMAssay Description:Inhibition of Opioid receptor mu 1 of guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Clinical Research Institute of Montreal

Curated by PDSP Ki Database
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 9.30nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  9.5nMAssay Description:Inhibition of DAMGO (Tyr-[D-Ala]-Gly-[NMe-Phe]-Gly-ol) binding to rat brain mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  9.53nMAssay Description:Displacement of [3H]DAMGO from Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  9.56nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  9.60nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Displayed 1 to 50 (of 125 total ) | Next | Last >>