BDBM50139360 CHEMBL161846::[2-(Benzothiazol-2-ylsulfanyl)-ethyl]-dimethyl-amine

SMILES CN(C)CCSc1nc2ccccc2s1

InChI Key InChIKey=KMWKXYYYWRNCEV-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50139360   

Target5-hydroxytryptamine receptor 7(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139360([2-(Benzothiazol-2-ylsulfanyl)-ethyl]-dimethyl-ami...)
Affinity DataKi:  84nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in CHO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139360([2-(Benzothiazol-2-ylsulfanyl)-ethyl]-dimethyl-ami...)
Affinity DataKi:  830nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1A receptor by the displacement of [3H]5-HT radioligand from the cloned receptor expressed in HeLa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139360([2-(Benzothiazol-2-ylsulfanyl)-ethyl]-dimethyl-ami...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity towards human dopamine receptor D2 by the displacement of [3H]spiperone radioligand from the cloned receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139360([2-(Benzothiazol-2-ylsulfanyl)-ethyl]-dimethyl-ami...)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 2A receptor by the displacement of [3H]ketanserin radioligand from the cloned receptor expressed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed