BDBM50149704 CHEMBL3771135

SMILES Cc1cc(C)c(CNC(=O)c2cc(Br)nc3n(ncc23)C2CCN(CC2)C(=O)OC(C)(C)C)c(=O)[nH]1

InChI Key InChIKey=YTMNEGGAZMYECL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50149704   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

Curated by ChEMBL
LigandPNGBDBM50149704(CHEMBL3771135)
Affinity DataIC50: 200nMAssay Description:Inhibition of methyltransferase activity of human EZH2 using chicken oligonucleotide as substrate by pull down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2017
Entry Details Article
PubMed