BDBM50153217 CHEMBL425359::N-(2-Diethylamino-ethyl)-4-[3-(4-trifluoromethyl-phenyl)-ureido]-benzamide

SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(cc2)C(F)(F)F)cc1

InChI Key InChIKey=OCLQJIUKSIDWNK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153217   

TargetMelanin-concentrating hormone receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50153217(N-(2-Diethylamino-ethyl)-4-[3-(4-trifluoromethyl-p...)
Affinity DataIC50: 5.30nMAssay Description:Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]MCH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50153217(N-(2-Diethylamino-ethyl)-4-[3-(4-trifluoromethyl-p...)
Affinity DataIC50: 170nMAssay Description:Antagonistic activity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using IP3 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed