BDBM50164772 (2S,5S)-5-Ethyl-4-methyl-piperazine-2-carboxylic acid [(R)-2-(4-tert-butylcarbamoyl-4-cyclohexyl-piperidin-1-yl)-1-(4-fluoro-benzyl)-2-oxo-ethyl]-amide; dihydrochloride::CHEMBL538567

SMILES CC[C@H]1CN[C@@H](CN1C)C(=O)N[C@H](Cc1ccc(F)cc1)C(=O)N1CCC(CC1)(C1CCCCC1)C(=O)NC(C)(C)C

InChI Key InChIKey=UTVJDBAFZSBXLX-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50164772   

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164772((2S,5S)-5-Ethyl-4-methyl-piperazine-2-carboxylic a...)
Affinity DataEC50:  2nMAssay Description:Inhibitory concentration to displace [125I]-NDP-alpha-MSH from human melanocortin 4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164772((2S,5S)-5-Ethyl-4-methyl-piperazine-2-carboxylic a...)
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration to displace [125I]NDP-alpha-MSH from human melanocortin 4 receptor expressed in CHO cells; Control 19 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164772((2S,5S)-5-Ethyl-4-methyl-piperazine-2-carboxylic a...)
Affinity DataEC50:  150nMAssay Description:Concentration of compound at 50% maximum cAMP accumulation mediated by human melanocortin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164772((2S,5S)-5-Ethyl-4-methyl-piperazine-2-carboxylic a...)
Affinity DataEC50:  450nMAssay Description:Concentration of compound at 50% maximum cAMP accumulation mediated by human melanocortin 5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed