BDBM50173658 1-(4-Fluoro-phenyl)-2-(4-hydroxy-phenyl)-3H-inden-5-ol::CHEMBL371236

SMILES Oc1ccc(cc1)C1=C(c2ccc(O)cc2C1)c1ccc(F)cc1

InChI Key InChIKey=VFNJKWBUAUKQIJ-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50173658   

TargetEstrogen receptor beta(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50173658(1-(4-Fluoro-phenyl)-2-(4-hydroxy-phenyl)-3H-inden-...)
Affinity DataKi:  2.80nMAssay Description:Antagonistic activity against estrogen receptor beta in presence of 0.1 nM estradiolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50173658(1-(4-Fluoro-phenyl)-2-(4-hydroxy-phenyl)-3H-inden-...)
Affinity DataEC50:  3.90nMAssay Description:Transcriptional activation of estrogen receptor alpha in U2OS cell using estrogen-regulated luciferase reporter gene plasmid upon incubation for 20-3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50173658(1-(4-Fluoro-phenyl)-2-(4-hydroxy-phenyl)-3H-inden-...)
Affinity DataEC50:  10nMAssay Description:Transcriptional activation of estrogen receptor beta in U2OS cell using estrogen-regulated luciferase reporter gene plasmid upon incubation for 20-30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed