BDBM50174002 CHEMBL370652::N-((S)-1-(4-(trifluoromethyl)benzyl)pyrrolidin-3-yl)-3-(thiophen-2-yl)benzamide

SMILES FC(F)(F)c1ccc(CN2CC[C@@H](C2)NC(=O)c2cccc(c2)-c2cccs2)cc1

InChI Key InChIKey=AWAXPOLEGZALIG-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50174002   

TargetD(4) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50174002(N-((S)-1-(4-(trifluoromethyl)benzyl)pyrrolidin-3-y...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]spiperone from cloned human dopamine D4.2 receptor in HEK298 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50174002(N-((S)-1-(4-(trifluoromethyl)benzyl)pyrrolidin-3-y...)
Affinity DataKi:  740nMAssay Description:Displacement of [3H]ketanserin from cloned human 5HT2A receptor in HEK298 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50174002(N-((S)-1-(4-(trifluoromethyl)benzyl)pyrrolidin-3-y...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine D2(short) receptor in rat pituitary GH4C1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed