BDBM50174718 CHEMBL200680::N-(6-(3-(3-(4-fluorobenzyl)-3,8-diaza-bicyclo[3.2.1]octan-8-yl)-3-oxoprop-1-enyl)quinolin-7-yl)acetamide

SMILES CC(=O)Nc1cc2ncccc2cc1\C=C\C(=O)N1C2CCC1CN(Cc1ccc(F)cc1)C2

InChI Key InChIKey=AHYXGZDCECWMIM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50174718   

TargetC-C chemokine receptor type 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50174718(N-(6-(3-(3-(4-fluorobenzyl)-3,8-diaza-bicyclo[3.2....)
Affinity DataIC50: 6nMAssay Description:Antagonistic activity at rat CCR1 in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50174718(N-(6-(3-(3-(4-fluorobenzyl)-3,8-diaza-bicyclo[3.2....)
Affinity DataIC50: 50nMAssay Description:Antagonistic activity at mouse CCR1 in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50174718(N-(6-(3-(3-(4-fluorobenzyl)-3,8-diaza-bicyclo[3.2....)
Affinity DataIC50: 150nMAssay Description:Antagonistic activity at human CCR1 in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed