BDBM50175474 3-{2-[4-(2-chloro-phenyl)-piperazin-1-yl]-ethyl}-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one::CHEMBL198696

SMILES CN1CCc2c(C1)sc1ncn(CCN3CCN(CC3)c3ccccc3Cl)c(=O)c21

InChI Key InChIKey=OUCJGZCXQWDKNF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50175474   

Target5-hydroxytryptamine receptor 1B(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50175474(3-{2-[4-(2-chloro-phenyl)-piperazin-1-yl]-ethyl}-7...)
Affinity DataKi:  1.70nMAssay Description:Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50175474(3-{2-[4-(2-chloro-phenyl)-piperazin-1-yl]-ethyl}-7...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [35S]GTP-gamma-S from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed