BDBM50178873 4-((3-cyano-6-(thiophen-2-yl)-4-(trifluoromethyl)pyridin-2-ylthio)methyl)benzoic acid::CHEMBL203287

SMILES OC(=O)c1ccc(CSc2nc(cc(c2C#N)C(F)(F)F)-c2cccs2)cc1

InChI Key InChIKey=ZCALTZJTUHPIBH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50178873   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178873(4-((3-cyano-6-(thiophen-2-yl)-4-(trifluoromethyl)p...)
Affinity DataIC50: 700nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50178873(4-((3-cyano-6-(thiophen-2-yl)-4-(trifluoromethyl)p...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of PDE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed