BDBM50179205 (2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamine::CHEMBL175596

SMILES C1c2ccccc2-c2n[nH]c(Nc3ccccc3)c12

InChI Key InChIKey=HXUODZKNCJWKGP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50179205   

TargetPlatelet-derived growth factor receptor beta(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179205((2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamine ...)
Affinity DataIC50: 317nMAssay Description:Inhibitory activity against PDGFRbeta kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Gakushuin University

Curated by ChEMBL
LigandPNGBDBM50179205((2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamine ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human HeLa cells expressing HRE-Luc after 12 hrs by luciferase reporter gene assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed