BDBM50181290 5-{3-[(S)-2-(4-biphenyl-3-yl-3-hydroxy-butyl)-5-oxo-pyrrolidin-1-yl]-propyl}-thiophene-2-carboxylic acid::CHEMBL382197

SMILES OC(CC[C@H]1CCC(=O)N1CCCc1ccc(s1)C(O)=O)Cc1cccc(c1)-c1ccccc1

InChI Key InChIKey=BCBYBNIDJGIOQL-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50181290   

LigandPNGBDBM50181290(5-{3-[(S)-2-(4-biphenyl-3-yl-3-hydroxy-butyl)-5-ox...)
Affinity DataIC50: 50nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50181290(5-{3-[(S)-2-(4-biphenyl-3-yl-3-hydroxy-butyl)-5-ox...)
Affinity DataIC50: 135nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50181290(5-{3-[(S)-2-(4-biphenyl-3-yl-3-hydroxy-butyl)-5-ox...)
Affinity DataEC50:  203nMAssay Description:Activity at rat EP4 transfected in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50181290(5-{3-[(S)-2-(4-biphenyl-3-yl-3-hydroxy-butyl)-5-ox...)
Affinity DataIC50: 1.86E+4nMAssay Description:Binding affinity to human EP1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50181290(5-{3-[(S)-2-(4-biphenyl-3-yl-3-hydroxy-butyl)-5-ox...)
Affinity DataIC50: 2.00E+4nMAssay Description:Binding affinity to human EP3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed