BDBM50182580 4-(2-pyrrolidin-1-yl-pentanoyl)benzonitrile::CHEMBL202518

SMILES CCCC(N1CCCC1)C(=O)c1ccc(cc1)C#N

InChI Key InChIKey=AQQRGNNYEPRIIF-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50182580   

TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182580(4-(2-pyrrolidin-1-yl-pentanoyl)benzonitrile | CHEM...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182580(4-(2-pyrrolidin-1-yl-pentanoyl)benzonitrile | CHEM...)
Affinity DataKi:  5.90E+3nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182580(4-(2-pyrrolidin-1-yl-pentanoyl)benzonitrile | CHEM...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182580(4-(2-pyrrolidin-1-yl-pentanoyl)benzonitrile | CHEM...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed