BDBM50184774 CHEMBL3799221

SMILES CCOC(Cn1nc(-c2cnc3[nH]ccc3c2)c2c(N)ncnc12)OCC

InChI Key InChIKey=PABMYTICQCKZAG-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50184774   

TargetSerine/threonine-protein kinase mTOR(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184774(CHEMBL3799221)
Affinity DataIC50: 328nMAssay Description:Inhibition of human mTOR using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase Yes(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184774(CHEMBL3799221)
Affinity DataIC50: 566nMAssay Description:Inhibition of human YES using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P] ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184774(CHEMBL3799221)
Affinity DataIC50: 598nMAssay Description:Inhibition of human RET using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184774(CHEMBL3799221)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of human ABL using EAIYAAPFAKKK as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184774(CHEMBL3799221)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of human FYN using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184774(CHEMBL3799221)
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of C-terminal His-tagged full length human SRC expressed in insect cells preincubated for 20 mins using poly[Glu,Tyr]4:1 as substrate meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184774(CHEMBL3799221)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PDGFRalpha using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50184774(CHEMBL3799221)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human KIT using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details Article
PubMed