BDBM50185276 CHEMBL3823872

SMILES CNC(=O)CN1CCN(CC1)c1ccc(Nc2ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n2)c(OC)c1

InChI Key InChIKey=VJWLMBVALMQEMA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50185276   

TargetALK tyrosine kinase receptor(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50185276(CHEMBL3823872)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human ALK using poly[Glu:Tyr] (4:1) as substrate and [gamma-33P]ATP measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50185276(CHEMBL3823872)
Affinity DataIC50: 125nMAssay Description:Inhibition of human IGF1R using KKKSPGEYVNIEFG as substrate and [gamma-33P]ATP measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50185276(CHEMBL3823872)
Affinity DataIC50: 459nMAssay Description:Inhibition of human InsR using myelin basic protein as substrate and [gamma-33P]ATP measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed