BDBM50185367 CHEMBL413871::H-[Trp-Arg-Nva-Arg-Tyr]3-NH2

SMILES CCC[C@H](NC(=O)[C@H](CCCN=C(/N)N)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCN=C(/N)N)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)N[C@@H](Cc4c[nH]c5ccccc45)C(=O)N[C@@H](CCCN=C(/N)N)C(=O)N[C@@H](CCC)C(=O)N[C@@H](CCCN=C(/N)N)C(=O)N[C@@H](Cc6ccc(O)cc6)C(=O)N[C@@H](Cc7c[nH]c8ccccc78)C(=O)N[C@@H](CCCN=C(/N)N)C(=O)N[C@@H](CCC)C(=O)N[C@@H](CCCN=C(/N)N)C(=O)N[C@@H](Cc9ccc(O)cc9)C(N)=O

InChI Key InChIKey=DRBRBJSYRQHXHE-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50185367   

TargetNeuropeptide Y receptor type 4(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50185367(H-[Trp-Arg-Nva-Arg-Tyr]3-NH2 | CHEMBL413871)
Affinity DataKi:  3.90nMAssay Description:Agonist activity at human NPY4 receptor in HEK293 cells by inhibition of forskolin-stimulated cAMP synthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50185367(H-[Trp-Arg-Nva-Arg-Tyr]3-NH2 | CHEMBL413871)
Affinity DataKi:  30nMAssay Description:Agonist activity at human NPY1 receptor in CHO cells by inhibition of forskolin-stimulated cAMP synthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50185367(H-[Trp-Arg-Nva-Arg-Tyr]3-NH2 | CHEMBL413871)
Affinity DataKi:  50nMAssay Description:Agonist activity at human NPY2 receptor in CHO cells by inhibition of forskolin-stimulated cAMP synthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50185367(H-[Trp-Arg-Nva-Arg-Tyr]3-NH2 | CHEMBL413871)
Affinity DataEC50:  230nMAssay Description:Agonist activity at human NPY4 receptor in HEK293 cells by inhibition of forskolin-stimulated cAMP synthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
University of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50185367(H-[Trp-Arg-Nva-Arg-Tyr]3-NH2 | CHEMBL413871)
Affinity DataEC50:  1.18E+3nMAssay Description:Agonist activity at human NPY2 receptor in CHO cells by inhibition of forskolin-stimulated cAMP synthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed