BDBM50188066 CHEMBL213302::N-(2-(1H-indol-3-yl)ethyl)-4-chloro-N-methylbenzamide

SMILES CN(CCc1c[nH]c2ccccc12)C(=O)c1ccc(Cl)cc1

InChI Key InChIKey=IEAKWXUPKMDFOG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50188066   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188066(N-(2-(1H-indol-3-yl)ethyl)-4-chloro-N-methylbenzam...)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of Cdk4/Cyclin D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188066(N-(2-(1H-indol-3-yl)ethyl)-4-chloro-N-methylbenzam...)
Affinity DataIC50: 3.80E+4nMAssay Description:Binding affinity to human CDK4/cyclinD1 using GST-pRB152 as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188066(N-(2-(1H-indol-3-yl)ethyl)-4-chloro-N-methylbenzam...)
Affinity DataIC50: 5.00E+5nMAssay Description:Binding affinity to human CDK1/cyclinB1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188066(N-(2-(1H-indol-3-yl)ethyl)-4-chloro-N-methylbenzam...)
Affinity DataIC50: 7.31E+5nMAssay Description:Inhibition of Cdk2/Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188066(N-(2-(1H-indol-3-yl)ethyl)-4-chloro-N-methylbenzam...)
Affinity DataIC50: 7.31E+5nMAssay Description:Binding affinity to human CDK2/cyclinA using GST-pRB152 as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188066(N-(2-(1H-indol-3-yl)ethyl)-4-chloro-N-methylbenzam...)
Affinity DataIC50: 1.00E+6nMAssay Description:Binding affinity to human CDK9/cyclinT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed