BDBM50188302 2-(1-(7-chloroquinolin-4-yl)-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid::CHEMBL213029

SMILES COc1ccc2n(c(C)c(CC(O)=O)c2c1)-c1ccnc2cc(Cl)ccc12

InChI Key InChIKey=VJXYIASUBZUHMU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50188302   

TargetProstaglandin G/H synthase 1(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50188302(2-(1-(7-chloroquinolin-4-yl)-5-methoxy-2-methyl-1H...)
Affinity DataIC50: 40nMAssay Description:Inhibition of COX1-mediated platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50188302(2-(1-(7-chloroquinolin-4-yl)-5-methoxy-2-methyl-1H...)
Affinity DataIC50: 180nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50188302(2-(1-(7-chloroquinolin-4-yl)-5-methoxy-2-methyl-1H...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition at recombinant human CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed