BDBM50192438 4-(2-chlorophenyl)-9-hydroxy-6-isopentylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::CHEMBL384831

SMILES CC(C)CCn1c2ccc(O)cc2c2c3C(=O)NC(=O)c3c(cc12)-c1ccccc1Cl

InChI Key InChIKey=DDMDDWMWTMOXPE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50192438   

TargetWee1-like protein kinase(Human)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50192438(4-(2-chlorophenyl)-9-hydroxy-6-isopentylpyrrolo[3,...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human Wee1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50192438(4-(2-chlorophenyl)-9-hydroxy-6-isopentylpyrrolo[3,...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human Wee1 in presence of 9.5 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50192438(4-(2-chlorophenyl)-9-hydroxy-6-isopentylpyrrolo[3,...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition at human Chk1 in presence of 4 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed