BDBM50194892 CHEMBL221175::N-(4-(methylsulfonyl)benzyl)-4-amino-5-cyano-6-(2-(dimethylamino)ethylamino)picolinamide

SMILES CN(C)CCNc1nc(cc(N)c1C#N)C(=O)NCc1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=FRDJNHPTNDWOFL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50194892   

TargetMitogen-activated protein kinase 8(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50194892(N-(4-(methylsulfonyl)benzyl)-4-amino-5-cyano-6-(2-...)
Affinity DataIC50: 7.29E+3nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50194892(N-(4-(methylsulfonyl)benzyl)-4-amino-5-cyano-6-(2-...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of JNK1 by ATF2 phosphorylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50194892(N-(4-(methylsulfonyl)benzyl)-4-amino-5-cyano-6-(2-...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of JNK2 by ATF2 phosphorylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed