BDBM50195952 CHEMBL374251::N-[(4R)-3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl]-2-{2-oxo-3-[4-(trifluoromethyl)pyrimidin-2-yl]-2,3-dihydro-1H-1,3-benzodiazol-1-yl}acetamide

SMILES CN1C(=O)NC(=O)[C@]11Cc2ccc(NC(=O)Cn3c4ccccc4n(-c4nccc(n4)C(F)(F)F)c3=O)cc2C1

InChI Key InChIKey=CBYMKRJSUMRSHK-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50195952   

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195952(N-[(4R)-3-methyl-2,5-dioxo-1',3'-dihydrospiro[imid...)
Affinity DataKi:  10nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195952(N-[(4R)-3-methyl-2,5-dioxo-1',3'-dihydrospiro[imid...)
Affinity DataIC50: 50nMAssay Description:Inhibition of CGRP-induced cAMP production in E10 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed