BDBM50204780 8-cyclohexylmethyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL240001

SMILES O=C1NCN(c2ccccc2)C11CCN(CC2CCCCC2)CC1

InChI Key InChIKey=QHWSFZBBZXHNKX-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50204780   

TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50204780(8-cyclohexylmethyl-1-phenyl-1,3,8-triaza-spiro[4.5...)
Affinity DataKi:  61nMAssay Description:Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50204780(8-cyclohexylmethyl-1-phenyl-1,3,8-triaza-spiro[4.5...)
Affinity DataKi:  517nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50204780(8-cyclohexylmethyl-1-phenyl-1,3,8-triaza-spiro[4.5...)
Affinity DataKi:  887nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50204780(8-cyclohexylmethyl-1-phenyl-1,3,8-triaza-spiro[4.5...)
Affinity DataKi:  7.37E+4nMAssay Description:Displacement of [3H]diprenorphine from human delta opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed