BDBM50206280 4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-morpholinoethyl)phenyl)pyrimidin-2-amine::4-ARYL-2-PHENYLAMINO PYRIMIDINE::CHEMBL233209

SMILES CC(C)(c1ccc(cc1)c2c(cnc(n2)Nc3ccc(cc3)CCN4CCOCC4)Cl)N

InChI Key InChIKey=CJSSYVIHFXDFFC-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50206280   

TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206280(4-ARYL-2-PHENYLAMINO PYRIMIDINE | 4-(4-(2-aminopro...)
Affinity DataIC50: 148nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206280(4-ARYL-2-PHENYLAMINO PYRIMIDINE | 4-(4-(2-aminopro...)
Affinity DataIC50: 2.77E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed