BDBM50207472 4-(4-aminophenyl)-1H-indazol-3-amine::4-(4-aminophenyl)-1H-indazol-3yl-amine::CHEMBL222778

SMILES Nc1n[nH]c2cccc(-c3ccc(N)cc3)c12

InChI Key InChIKey=KHQLSBOHZQJRPC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50207472   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207472(4-(4-aminophenyl)-1H-indazol-3yl-amine | 4-(4-amin...)
Affinity DataIC50: 43nMAssay Description:Inhibition of FLT3 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207472(4-(4-aminophenyl)-1H-indazol-3yl-amine | 4-(4-amin...)
Affinity DataIC50: 4.79E+3nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207472(4-(4-aminophenyl)-1H-indazol-3yl-amine | 4-(4-amin...)
Affinity DataIC50: 7.36E+3nMAssay Description:Inhibition of c-Kit by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207472(4-(4-aminophenyl)-1H-indazol-3yl-amine | 4-(4-amin...)
Affinity DataIC50: 7.36E+3nMAssay Description:Inhibition of c-Kit by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed