BDBM50207483 CHEMBL222315::N-(4-(3-amino-1H-indazol-4-yl)phenyl)cyclohexanecarboxamide::N-[4-(3-amino-1H-indazol-4-yl)-phenyl]-N'-cyclohexylurea

SMILES Nc1n[nH]c2cccc(-c3ccc(NC(=O)C4CCCCC4)cc3)c12

InChI Key InChIKey=ICAGRINJJFYTOB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50207483   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207483(N-[4-(3-amino-1H-indazol-4-yl)-phenyl]-N'-cyclohex...)
Affinity DataIC50: 13nMAssay Description:Inhibition of FLT3 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207483(N-[4-(3-amino-1H-indazol-4-yl)-phenyl]-N'-cyclohex...)
Affinity DataIC50: 86nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50207483(N-[4-(3-amino-1H-indazol-4-yl)-phenyl]-N'-cyclohex...)
Affinity DataIC50: 152nMAssay Description:Inhibition of c-Kit by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50207483(N-[4-(3-amino-1H-indazol-4-yl)-phenyl]-N'-cyclohex...)
Affinity DataIC50: 152nMAssay Description:Inhibition of c-Kit by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed