BDBM50209237 6-bromo-1H-indazole::CHEMBL247365

SMILES Brc1ccc2cn[nH]c2c1

InChI Key InChIKey=WMKDUJVLNZANRN-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50209237   

TargetMicrotubule-associated protein 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50209237(6-bromo-1H-indazole | CHEMBL247365)
Affinity DataIC50: 1.10E+3nMAssay Description:Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2017
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Uned

Curated by ChEMBL
LigandPNGBDBM50209237(6-bromo-1H-indazole | CHEMBL247365)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of NOS1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Upres-Ea 3915

Curated by ChEMBL
LigandPNGBDBM50209237(6-bromo-1H-indazole | CHEMBL247365)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of rat neuronal NOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM50209237(6-bromo-1H-indazole | CHEMBL247365)
Affinity DataKd:  3.80E+4nMAssay Description:Binding affinity to human DYRK1A (127 to 485 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as dissociation constant by isothermal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed