BDBM50220689 (R)-N-((S)-1-(4-sec-butyl-4-((1-methyl-1H-tetrazol-5-yl)methyl)piperidin-1-yl)-3-(4-chlorophenyl)-1-oxopropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL400456

SMILES CCC(C)C1(Cc2nnnn2C)CCN(CC1)C(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1

InChI Key InChIKey=AWOJJPZZOHGJMY-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50220689   

TargetMelanocortin receptor 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50220689((R)-N-((S)-1-(4-sec-butyl-4-((1-methyl-1H-tetrazol...)
Affinity DataIC50: 3.70nMAssay Description:Binding affinity to human MC4RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50220689((R)-N-((S)-1-(4-sec-butyl-4-((1-methyl-1H-tetrazol...)
Affinity DataEC50:  3.90nMAssay Description:Antagonist activity at human MC4R assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50220689((R)-N-((S)-1-(4-sec-butyl-4-((1-methyl-1H-tetrazol...)
Affinity DataEC50:  250nMAssay Description:Antagonist activity at human MC5R assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50220689((R)-N-((S)-1-(4-sec-butyl-4-((1-methyl-1H-tetrazol...)
Affinity DataEC50:  263nMAssay Description:Antagonist activity at human MC3R assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed