BDBM50231726 2-(adamantan-1-ylamino)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinoline-3-carbonitrile::CHEMBL401331

SMILES CC1(C)CC(=O)c2cc(C#N)c(NC34CC5CC(CC(C5)C3)C4)nc2C1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231726   

TargetMetabotropic glutamate receptor 1(Rat)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50231726(2-(adamantan-1-ylamino)-7,7-dimethyl-5-oxo-5,6,7,8...)
Affinity DataIC50: 4.10E+4nMAssay Description:Antagonist activity at rat mGluR1 expressed in cerebellar granule cells assessed as accumulation of [3H]inositol phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed