BDBM50234465 CHEMBL270083::cis-2-aminocyclohexylcarbamoylphosphonic acid

SMILES N[C@H]1CCCC[C@H]1NC(=O)P(O)(O)=O

InChI Key InChIKey=XHCXISPZIHYKQD-UHFFFAOYSA-N

Data  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50234465   

Target72 kDa type IV collagenase(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50234465(cis-2-aminocyclohexylcarbamoylphosphonic acid | CH...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human recombinant MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50234465(cis-2-aminocyclohexylcarbamoylphosphonic acid | CH...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50234465(cis-2-aminocyclohexylcarbamoylphosphonic acid | CH...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50234465(cis-2-aminocyclohexylcarbamoylphosphonic acid | CH...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50234465(cis-2-aminocyclohexylcarbamoylphosphonic acid | CH...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50234465(cis-2-aminocyclohexylcarbamoylphosphonic acid | CH...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50234465(cis-2-aminocyclohexylcarbamoylphosphonic acid | CH...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50234465(cis-2-aminocyclohexylcarbamoylphosphonic acid | CH...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50234465(cis-2-aminocyclohexylcarbamoylphosphonic acid | CH...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50234465(cis-2-aminocyclohexylcarbamoylphosphonic acid | CH...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50234465(cis-2-aminocyclohexylcarbamoylphosphonic acid | CH...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50234465(cis-2-aminocyclohexylcarbamoylphosphonic acid | CH...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50234465(cis-2-aminocyclohexylcarbamoylphosphonic acid | CH...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50234465(cis-2-aminocyclohexylcarbamoylphosphonic acid | CH...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50234465(cis-2-aminocyclohexylcarbamoylphosphonic acid | CH...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50234465(cis-2-aminocyclohexylcarbamoylphosphonic acid | CH...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed