BDBM50243938 (trans)-1-(3,4-dichlorophenyl)-6-methyl-3-aza-bicyclo[3.1.0]hexane::CHEMBL521058

SMILES C[C@H]1[C@H]2CNC[C@@]12c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=AYVHIUIIRXDSCH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243938   

TargetSodium-dependent serotonin transporter(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243938((trans)-1-(3,4-dichlorophenyl)-6-methyl-3-aza-bicy...)
Affinity DataIC50: 200nMAssay Description:Inhibition of serotonin uptake at SERT in rat brain synaptosomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243938((trans)-1-(3,4-dichlorophenyl)-6-methyl-3-aza-bicy...)
Affinity DataIC50: 500nMAssay Description:Inhibition of dopamine uptake at cloned DAT in rat brain synaptosomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243938((trans)-1-(3,4-dichlorophenyl)-6-methyl-3-aza-bicy...)
Affinity DataIC50: 500nMAssay Description:Inhibition of norepinephrine uptake at NET in rat brain synaptosomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed