BDBM50244831 4-((3-(2,3-dimethylphenyl)-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)benzoic acid::CHEMBL461575

SMILES Cc1cccc(N2C(=S)S\C(=C/c3ccc(cc3)C(O)=O)C2=O)c1C

InChI Key InChIKey=BRKYTJFUNROSCM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50244831   

TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50244831(4-((3-(2,3-dimethylphenyl)-4-oxo-2-thioxothiazolid...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human wild type CFTR expressed in rat FRT cells assessed as chloride current by short-circuit current measurementsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed