BDBM50252639 CHEMBL493264::N,N-dimethyl(2-(4-(methylthio)phenylthio)phenyl)methanamine

SMILES CSc1ccc(Sc2ccccc2CN(C)C)cc1

InChI Key InChIKey=DVFKWYNNNBWGRC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252639   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50252639(N,N-dimethyl(2-(4-(methylthio)phenylthio)phenyl)me...)
Affinity DataIC50: 22nMAssay Description:Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252639(N,N-dimethyl(2-(4-(methylthio)phenylthio)phenyl)me...)
Affinity DataIC50: 640nMAssay Description:Inhibition of [3H]NA reuptake in human noradrenaline transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50252639(N,N-dimethyl(2-(4-(methylthio)phenylthio)phenyl)me...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of [3H]DA reuptake at human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed