BDBM50254972 1-Benzyl-8-ethyl-7-methyl-3-propyl-1H,8H-imidazo[2,1-f]-purine-2,4-dione::CHEMBL481383

SMILES CCCn1c(=O)n(Cc2ccccc2)c2nc3n(CC)c(C)cn3c2c1=O

InChI Key InChIKey=ABHYOLCRTCYDDO-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50254972   

TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50254972(1-Benzyl-8-ethyl-7-methyl-3-propyl-1H,8H-imidazo[2...)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]MRE3008F20 from human cloned adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50254972(1-Benzyl-8-ethyl-7-methyl-3-propyl-1H,8H-imidazo[2...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]DPCPX from human cloned adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50254972(1-Benzyl-8-ethyl-7-methyl-3-propyl-1H,8H-imidazo[2...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human cloned adenosine A2B cells expressed in CHO cells assessed as inhibition of NECA-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50254972(1-Benzyl-8-ethyl-7-methyl-3-propyl-1H,8H-imidazo[2...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]ZM241385 from human cloned adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed