BDBM50255124 3-(1-(3,4-difluorobenzyl)-3a-methyl-2-oxo-2,3,3a,4,5,6-hexahydro-1H-indol-7-yl)-N-(3,4-difluorophenylsulfonyl)acrylamide::CHEMBL479664

SMILES CC12CC(=O)N(Cc3ccc(F)c(F)c3)C1=C(CCC2)\C=C\C(=O)NS(=O)(=O)c1ccc(F)c(F)c1

InChI Key InChIKey=HQYWCTNHMZXESG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50255124   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255124(3-(1-(3,4-difluorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 9.40nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255124(3-(1-(3,4-difluorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 2.30E+3nMAssay Description:Binding affinity to human EP2 receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255124(3-(1-(3,4-difluorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 7.70E+3nMAssay Description:Binding affinity to human EP4 receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255124(3-(1-(3,4-difluorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 1.64E+4nMAssay Description:Binding affinity to human FP receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed