BDBM50256510 CHEMBL500977::N-(5-ethyl-1,3,4-thiadiazol-2-yl)sulfamide

SMILES CCc1nnc(NS(N)(=O)=O)s1

InChI Key InChIKey=HVRGNGCSIVHKLU-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50256510   

TargetCarbonic anhydrase 2(Human)
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM50256510(N-(5-ethyl-1,3,4-thiadiazol-2-yl)sulfamide | CHEMB...)
Affinity DataKi:  950nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 2 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM50256510(N-(5-ethyl-1,3,4-thiadiazol-2-yl)sulfamide | CHEMB...)
Affinity DataKi:  7.01E+3nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 1 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM50256510(N-(5-ethyl-1,3,4-thiadiazol-2-yl)sulfamide | CHEMB...)
Affinity DataKi:  8.64E+3nMAssay Description:Inhibition of truncated human cloned membrane-associated carbonic anhydrase 4 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM50256510(N-(5-ethyl-1,3,4-thiadiazol-2-yl)sulfamide | CHEMB...)
Affinity DataKi:  1.87E+4nMAssay Description:Inhibition of full length human recombinant mitochondrial carbonic anhydrase 5A pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM50256510(N-(5-ethyl-1,3,4-thiadiazol-2-yl)sulfamide | CHEMB...)
Affinity DataKi:  6.30E+4nMAssay Description:Inhibition of full length human recombinant mitochondrial carbonic anhydrase 5B preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed