BDBM50262506 3-((S)-3-((3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)methyl)pyrrolidin-1-yl)quinoline::CHEMBL515648

SMILES Fc1ccc(-c2noc(C[C@@H]3CCN(C3)c3cnc4ccccc4c3)n2)c(Cl)c1

InChI Key InChIKey=AEKOYIYPZKHXPB-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50262506   

TargetCannabinoid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50262506(3-((S)-3-((3-(2-chloro-4-fluorophenyl)-1,2,4-oxadi...)
Affinity DataEC50:  86nMAssay Description:Agonist activity at human CB2 receptor expressed in insect Sf9 cells assessed as effect on Eu-GTP bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50262506(3-((S)-3-((3-(2-chloro-4-fluorophenyl)-1,2,4-oxadi...)
Affinity DataEC50:  1.27E+3nMAssay Description:Agonist activity at human CB1 receptor expressed in insect Sf9 cells assessed as effect on Eu-GTP bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50262506(3-((S)-3-((3-(2-chloro-4-fluorophenyl)-1,2,4-oxadi...)
Affinity DataEC50: >2.00E+3nMAssay Description:Agonist activity at human CB1 receptor assessed as inhibition of forskolin-induced increase in intracellular cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50262506(3-((S)-3-((3-(2-chloro-4-fluorophenyl)-1,2,4-oxadi...)
Affinity DataEC50: >2.00E+3nMAssay Description:Agonist activity at human CB2 receptor assessed as inhibition of forskolin-induced increase in intracellular cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed