BDBM50272880 2-((S)-7-((R)-2-(3-chlorophenyl)-2-hydroxyethylamino)-5,6,7,8-tetrahydronaphthalen-2-yloxy)acetic acid::CHEMBL498305

SMILES O[C@@H](CN[C@H]1CCc2ccc(OCC(O)=O)cc2C1)c1cccc(Cl)c1

InChI Key InChIKey=PLYWAKPAFSZPAL-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50272880   

TargetBeta-3 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50272880(2-((S)-7-((R)-2-(3-chlorophenyl)-2-hydroxyethylami...)
Affinity DataEC50:  39nMAssay Description:Agonist activity at human cloned beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50272880(2-((S)-7-((R)-2-(3-chlorophenyl)-2-hydroxyethylami...)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at human cloned beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50272880(2-((S)-7-((R)-2-(3-chlorophenyl)-2-hydroxyethylami...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed