BDBM50280887 CHEMBL4176043

SMILES OC(=O)[C@@H]1CCCN(CCC#Cc2cccc(c2)\N=N\c2ccccc2)C1

InChI Key InChIKey=ICLXFBQEDLKKEJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50280887   

TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50280887(CHEMBL4176043)
Affinity DataIC50: 2.24E+4nMAssay Description:Inhibition of mouse GAT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50280887(CHEMBL4176043)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse GAT2 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50280887(CHEMBL4176043)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse GAT4 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2020
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50280887(CHEMBL4176043)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse GAT3 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2020
Entry Details Article
PubMed