BDBM50283545 CHEMBL4162340

SMILES N[C@@H]1CCCN(C1)c1nc2cc[nH]c2c(=O)n1Cc1cc(F)ccc1C#N

InChI Key InChIKey=QXHPVHPQZWZDSP-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50283545   

TargetDipeptidyl peptidase 4(Human)
The First Affiliated Hospital of Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50283545(CHEMBL4162340)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human DPP4 using Gly-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 5 to 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
The First Affiliated Hospital of Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50283545(CHEMBL4162340)
Affinity DataKi:  2.90nMAssay Description:Reversible mixed-type inhibition of human DPP4 using Gly-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
The First Affiliated Hospital of Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50283545(CHEMBL4162340)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of DPP9 (unknown origin) using Gly-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 5 to 10 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
The First Affiliated Hospital of Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50283545(CHEMBL4162340)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of DPP8 (unknown origin) using Gly-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 5 to 10 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed