BDBM50287334 1N-[4-cyclopropylmethyl-10-hydroxy-14-oxo-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-17-yl]-2-chloroacrylamide::CHEMBL288178

SMILES Oc1ccc2CC3N(CC4CC4)CCC45[C@@H](Oc1c24)C(=O)CC[C@@]35NC(=O)C(Cl)=C

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50287334   

TargetMu-type opioid receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50287334(1N-[4-cyclopropylmethyl-10-hydroxy-14-oxo-(13R,17S...)
Affinity DataIC50: 24nMAssay Description:Compound was tested for Inhibition of [3H]DAMGO (0.25 nM) binding to mu receptor from bovine striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287334(1N-[4-cyclopropylmethyl-10-hydroxy-14-oxo-(13R,17S...)
Affinity DataIC50: 177nMAssay Description:Compound was tested for Inhibition of 9 (1 nM) binding to Opioid receptor delta 1 from bovine striatal MembranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287334(1N-[4-cyclopropylmethyl-10-hydroxy-14-oxo-(13R,17S...)
Affinity DataIC50: 501nMAssay Description:Compound was tested for Inhibition of [3H]-DPDPE (0.2 nM) binding to Opioid receptor kappa 1 from bovine striatal MembranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article