BDBM50294258 CHEMBL541226::rac-4-((2,3-dichlorophenoxy)(phenyl)methyl)piperidine

SMILES Clc1cccc(OC(C2CCNCC2)c2ccccc2)c1Cl

InChI Key InChIKey=AMLGZPQHVSFYSD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50294258   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50294258(rac-4-((2,3-dichlorophenoxy)(phenyl)methyl)piperid...)
Affinity DataIC50: 8nMAssay Description:Inhibition of [3H]5-HT uptake at human 5HTT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
LigandPNGBDBM50294258(rac-4-((2,3-dichlorophenoxy)(phenyl)methyl)piperid...)
Affinity DataIC50: 16nMAssay Description:Inhibition of [3H]NA uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50294258(rac-4-((2,3-dichlorophenoxy)(phenyl)methyl)piperid...)
Affinity DataIC50: 200nMAssay Description:Inhibition of [3H]DA uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
LigandPNGBDBM50294258(rac-4-((2,3-dichlorophenoxy)(phenyl)methyl)piperid...)
Affinity DataIC50: 950nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed