BDBM50296442 5-(2-methyl-3-phenylallylidene)-2-(phenylamino)thiazol-4(5H)-one::CHEMBL556292

SMILES CC(C=C1SC(Nc2cc(Cl)cc(Cl)c2)=NC1=O)=Cc1ccccc1

InChI Key InChIKey=GOVDXADQNGZDMM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296442   

TargetM-phase inducer phosphatase 2(Human)
Sejong University

Curated by ChEMBL
LigandPNGBDBM50296442(5-(2-methyl-3-phenylallylidene)-2-(phenylamino)thi...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of N-terminal 6xHis-tagged (378-566) catalytic domain of Cdc25B expressed in Escherichia coli after 20 mins by by fluorescent plate reader...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Sejong University

Curated by ChEMBL
LigandPNGBDBM50296442(5-(2-methyl-3-phenylallylidene)-2-(phenylamino)thi...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of N-terminal 6xHis-tagged human Cdc25A (336-523) catalytic domain expressed in Escherichia coli after 20 mins by fluorescent plate reader...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed