BDBM50296959 3-(cyclohexyloxy)-4'-((S)-3-hydroxy-2-((R)-2-hydroxy-2-phenylethylamino)propyl)-N-(methylsulfonyl)biphenyl-4-carboxamide::CHEMBL559486

SMILES CS(=O)(=O)NC(=O)c1ccc(cc1OC1CCCCC1)-c1ccc(C[C@@H](CO)NC[C@H](O)c2ccccc2)cc1

InChI Key InChIKey=AYJDIOYHPHNQIK-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296959   

TargetBeta-3 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50296959(3-(cyclohexyloxy)-4'-((S)-3-hydroxy-2-((R)-2-hydro...)
Affinity DataEC50:  0.820nMAssay Description:Agonist activity at human recombinant adrenergic beta3 receptor expressed in CHO cells assessed as stimulation of cAMP level after 1 hr by enzyme imm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50296959(3-(cyclohexyloxy)-4'-((S)-3-hydroxy-2-((R)-2-hydro...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human recombinant adrenergic beta-1 receptor expressed in CHO cells assessed as stimulation of cAMP level after 1 hr by enzyme im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed