BDBM50299980 (R)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)ethyl]-4-(4-methoxy-phenyl)-2-imidazolidinone::CHEMBL569185

SMILES COc1ccc(CCN2[C@@H](CN(NS(C)(=O)=O)C2=O)c2ccc(OC)cc2)cc1

InChI Key InChIKey=GFFIHDXPUGXVGG-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50299980   

LigandPNGBDBM50299980((R)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 480nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299980((R)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of Kv1.3 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299980((R)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 2.66E+3nMAssay Description:Inhibition of Kv1.1 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299980((R)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 3.87E+3nMAssay Description:Inhibition of Kv4.3 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299980((R)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of human ERG by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299980((R)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 2.34E+4nMAssay Description:Inhibition of Cav1.3 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50299980((R)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Nav1.5 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299980((R)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Cav1.2 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50299980((R)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50299980((R)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50299980((R)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)...)
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed